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Endoscopic hemostat 로고
Innovative Hemostatic Systems for Endoscopy

Just Spray It ! Endoscopic hemostatic system for GI bleeding

Brochure
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Nexpowder is a powdery wound dressing for endoscopies made of biocompatible polymer, used for gastrointestinal bleeding.
It is a convenient and safe product that can be used where the bleed is occurring without direct contact to the tissue, regardless of the bleeding location.
Nexpowder is sprayed through the endoscope, and when it comes in contact with water, as well as blood, gelation occurs; physically applying pressure
to the wound to prevent bleeding.
This adhesive gel also protects the wound, prevents contamination, and loss of body fluids that may occur through the wound.
The gel removes itself and is excreted within 1 to 3 days.

Overview
Indication

Nexpowder is a product used for wounds and bleeding sites during hemorrhagic digestive ulcers,
endoscopic mucosal resection (EMR), and endoscopic submucosal dissection (ESD) procedures.
Nexpowder prevents contamination of the affected area, protects wounds, and emits a hemostatic effect.

Features
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Hemostatic effect
immediately after use

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Low rate of re-bleeding

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Convenient to use

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No precise targeting required

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Low rate of clogging

How to use
  • Best practice
  • Make sure the valve is closed after connecting the catheter to spray body.

  • Be sure to turn on the power before inserting the catheter into the endoscope channel.

  • Do not place the catheter directly in contact with the bleeding site.

  • Do not aspirate while catheter is in the accessory channel.

Clinical outcomes

Immediate
hemostasis rate1

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The adhesive
Force of other
Hemostatic sprays2

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Rebleeding
rate3

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NexpowderTM has a high success rate for initial hemostasis in refractory upper gastrointestinal bleeding and is effective in prevention of rebleeding1)

Video play

Initial hemostasis 16 out of 17 patients (94%).

Rebleeding within 30 days was seen in 3 out of 16 patients (19%)

Remnants of the gel was evident in 11 out of 16 patients (69%) at the second examination after 24 hours.

NexpowderTM can be effective for treatment of nonvariceal upper gastrointestinal bleeding as monotherapy and preventing rebleeding3)

Immediate hemostasis was achieved in 54 of 56 patients (96.4%)

The re-bleeding rate within 30 days was 3.7% (2/54 patients)

No adverse event related to use of Nexpowder occurred.

NexpowderTM is considered an effective salvage therapy or even monotherapy for GI tumor bleeding with high immediate hemostasis and low rebleeding rate4)

Immediate hemostasis occurred in 40 out of 41 patients (97.5%)

Overall rebleeding rates at 7 and 28 days after hemostasis were 7.5% (3 of 40 patients) and 22.5% (9/40 patients)

The initial hemostasis success rate of conventional endoscopic therapy for tumor bleeding ranges from 31~40%
and the short-term rebleeding rate is about 80%.

No adverse event related to use of Nexpowder occurred.

  • Case videos by Medtronic
  • Dr. Beyna's experience with Nexpowder™

    Dr. Repici’s experience with Nexpowder™

  • ©2021 Medtronic. All rights reserved. Used with the permission of Medtronic.


Global partnership
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화살표
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Building a strategic
partnership for
innovation
in GI endoscopy

Ordering information

* 1 procedure kit

Product Name Reference No. Specifications Quantity
Nexpowder UI-EWD3 3g 1ea
Catheter EU-2522 2.5mm/220cm 1ea
Spray body UIPSD04 1ea 1ea
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References
01

Park JS, Bang BW, Hong SJ, et al. Efficacy of a novel hemostatic adhesive powder in patients with refractory upper gastrointestinal bleeding: A pilot study. Endoscopy. 2019 May;51(5):458-462

02

Bang B, Lee E, Maeng J, et al. Efficacy of a novel endoscopically deliverable mucoadhesive hemostatic powder in an acute gastric bleeding porcine model. PLoS One. 2019 Jun 11;14(6)e0216829

03

Park JS, Kim HK, Shin YW, et al. Novel hemostatic adhesive powder for nonvariceal upper gastrointestinal bleeding. Endoscopy International Open. 2019 Dec;7(12):E1763-E1767

04

J Shin et al. Efficacy of a novel hemostatic adhesive powder in patients with upper gastrointestinal tumor bleeding https://doi.org/10.1186/s12876-021-01611-0 Published